http://jmcrr.in/index.php/jmcrr/issue/feed Journal of Medical Care Research and Review 2019-03-28T06:38:44+00:00 Open Journal Systems <p><em>Journal of Medical Care Research and Review&nbsp;</em>&nbsp;has been&nbsp; force in the area of health services research. &nbsp;Journal's focus has expanded to reflect the growth of the field and the increasing importance of health services research -- while still maintaining the high standards that have kept&nbsp;&nbsp;<em>Journal of&nbsp;</em>&nbsp;<em>Medical Care Research and Review&nbsp;</em>at the forefront of health care research for over half a century.&nbsp;</p> <p align="left"><em>Journal of Medical Care Research and Review</em>&nbsp;covers timely aspects of health care such as:</p> <ul type="disc"> <li class="show"> <div align="left">Evaluation of the impact of changes in health policy and practice</div> </li> <li class="show"> <div align="left">Health insurance markets and the impact of health reform</div> </li> <li class="show"> <div align="left">Health Information Technology adoption and application in health delivery</div> </li> <li class="show"> <div align="left">Impact of competition and regulation on health care markets and providers</div> </li> <li class="show"> <div align="left">Health care disparities in access, treatment, and outcomes</div> </li> <li class="show"> <div align="left">Patient safety and quality of care</div> </li> <li class="show"> <div align="left">Health care workforce issues and primary care capacity</div> </li> <li class="show"> <div align="left">Patient engagement in health care decision-making</div> </li> <li class="show"> <div align="left">Economics and financial issues in health care delivery</div> </li> <li class="show"> <div align="left">Organizational structure and behavior of health organizations</div> </li> <li class="show"> <div align="left">Comparative effectiveness analysis</div> </li> </ul> http://jmcrr.in/index.php/jmcrr/article/view/35 Assessment of iron Parameters and Transient Elastography (FibroScan) Pattern amongPatients with Chronic Viral Hepatitis Infection in Jos, Nigeria 2019-03-28T06:38:44+00:00 AkinolaOyekemi I jmcrr2014@rediffmail.com Salawu Lateef jmcrr2014@rediffmail.com EgesieOchaka J jmcrr2014@rediffmail.com Okeke Edith N jmcrr2014@rediffmail.com Damulak Obadiah D jmcrr2014@rediffmail.com Imoh Lucius C jmcrr2014@rediffmail.com Akor Emmanuel A jmcrr2014@rediffmail.com <p><strong><em>Background:</em></strong>The long-termeffect of excess iron deposition in the liver include fibrosis and cirrhosis which may progress to hepatocellular carcinoma. We assessed iron parameters among patients with chronic viral hepatitis B and C infection (CVHBI; CVHCI) to determineif any correlation existed with the degree of fibrosis in the liver.</p> <p><strong><em>Methods</em></strong><em>:</em> A cross-sectional descriptive study was carried out on 186 patients, made up of 132 patients withCVHBI and 54 patients with CVHCI. Serum ferritin and C-reactive protein were done by ELISA, serum iron and total iron binding capacity (TIBC) by colorimetric technique while transferrin saturation (Tsat) was calculated using serum iron and TIBC values. Liver fibrosis was assessed using fibroscan.Obtained data wereanalysed using SPSS version 20 and p values &lt; 0.05 were considered statistically significant.&nbsp;</p> <p><strong><em>Results</em></strong><em>:</em> The mean values for serum ferritin, iron, TIBC and Tsat were 218.1±325.6µg/L, 25.1±22.8µmol/L, 71.13 ± 35.92µmol/L and 45.2 ± 49.9% respectively. There were no significant differences in iron parameters between patients with CVHBI and CVHCI. Elevated serum ferritin was found in 15.2% and 20.4% of CHBVI and CHCVI patients respectively; while an elevated Tsat was seen in 22.7% and 24.1% of CHBVI and CHCVI patients respectively. Using a combination of elevated serum ferritin and Tsat, the prevalence of iron overload was found to be1.6%. Fibroscan scores did not differ significantly between patients with orwithout elevated iron parameters.</p> <p><strong><em>Conclusion</em></strong><em>:</em>Chronic viral hepatitis infection is associated elevated iron parameters though withminimal effect on liver fibrosis.</p> <p><strong><em>Conflict of interest</em></strong><em>:</em> Nil</p> 2019-03-28T00:00:00+00:00 ##submission.copyrightStatement##